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New F-Gas Regulation: INNEXIS Helps Companies Make a Smooth Transition

With the new EU Regulation on fluorinated greenhouse gases (F-gases), the reduction of fluorinated greenhouse gases is taking center stage more than ever. The regulations entail far-reaching changes for operators of refrigeration and air-conditioning systems—from stricter documentation requirements and new bans to profound adjustments in technology and planning.

As an experienced operator of Pharma & Life Science Parks in Europe, INNEXIS guides companies safely through this transition.

Focus: Sustainable reduction of emissions

The regulation aims to significantly reduce emissions of fluorinated greenhouse gases over the long term. Among other things, it includes:

  • Emissions limits and reduced use of F-gas refrigerants

  • Expansion of recovery, recycling, and certified training programs

  • Strict requirements for documentation and operator responsibilities

The central element is the so-called phase-down: By 2050, the volume of vehicles put on the road is to be reduced by 90% compared to 2015—with significant tightening of regulations beginning as early as 2030.

New bans starting in 2026 and 2032

The upcoming bans are particularly relevant for operators:

  • Effective January 1, 2026: No use of refrigerants with a GWP greater than 2,500 in air conditioning systems

  • Effective January 1, 2032: No use of refrigerants with a GWP greater than 750

  • Transitional periods apply to recycled/reprocessed refrigerants until 2031

This significantly tightens the limits on Global Warming Potential (GWP)—another step toward more climate-friendly solutions.

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Alternative Refrigerants: Future-Proof Options

As regulations become stricter, the demands on refrigeration system operators are increasing. INNEXIS helps companies evaluate and transition to alternative refrigerants—from short-term retrofit solutions to new systems. The most important alternatives include:

Long-term options:

  • CO₂ (R744)

  • Propane (R290)

  • Ammonia (R717)

Medium-term alternatives:

  • R454c

  • R152a

  • R1234yf

Depending on the facility, various technical, safety-related, and economic factors must be taken into account—a careful case-by-case assessment is essential.

INNEXIS Engineering: Comprehensive support throughout the entire plant lifecycle

With over 25 years of experience in the life sciences industry, INNEXIS offers comprehensive engineering solutions for the retrofitting and new construction of refrigeration systems. These include, among other things:

  • Concept Development and Planning

  • Refrigeration Systems and Custom Fabrication

  • Initial and Retraining

  • Calibration and leak testing in accordance with the EU Regulation on fluorinated greenhouse gases (F-gases)

  • Retrofitting and Modification of Existing Systems

  • Maintenance & Inspection in accordance with VDMA 24186

All technical and regulatory requirements are taken into account from the very beginning—ensuring efficient, GxP-compliant, and future-proof processes.

Are you planning projects or do you need assistance?

If you have any questions regarding F-gas regulations, refrigeration systems, or technical solutions, our team is always available to assist you.

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